Published in 2008

Dynamic adaptation of tendon and muscle connective tissue to mechanical loading

Mackey, A. L., Heinemeier, K. M., Koskinen, S. O. A. & Kjaer, M., 2008, I: Connective Tissue Research. 49, 3, s. 165-8 4 s.

Publikation: Bidrag til tidsskriftReviewpeer review

Early interim PET scan in Hodgkin lymphoma: where do we stand?

Gallamini, A., Hutchings, M., Avigdor, A. & Polliack, A., apr. 2008, I: Leukemia and Lymphoma. 49, 4, s. 659-62 4 s.

Publikation: Bidrag til tidsskriftReviewpeer review

Effects of a perioperative smoking cessation intervention on postoperative complications: a randomized trial

Lindström, D., Sadr Azodi, O., Wladis, A., Tønnesen, H., Linder, S., Nåsell, H., Ponzer, S. & Adami, J., 1 nov. 2008, I: Annals of Surgery. 248, 5, s. 739-45 7 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

To determine whether an intervention with smoking cessation starting 4 weeks before general and orthopedic surgery would reduce the frequency of postoperative complications.
Originalsprog Engelsk
Tidsskrift Annals of Surgery
Vol/bind 248
Udgave nummer 5
Sider (fra-til) 739-45
Antal sider 7
ISSN 0003-4932
DOI
Status Udgivet - 1 nov. 2008

Graft rejection after hematopoietic cell transplantation with nonmyeloablative conditioning

Masmas, T. N., Petersen, S. L., Madsen, H. O., Ryder, L. P., Kornblit, B., Svejgaard, A., Andersen, P., Dickmeiss, E. & Vindeløv, L. L., jul. 2008, I: American Journal of Hematology. 83, 7, s. 563-9 7 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Health service interventions targeting relatives of heart patients: a review of the literature

Nissen, N. K., Madsen, M. & Olsen Zwisler, A-D., nov. 2008, I: Scandinavian Journal of Public Health. Supplement. 36, 8, s. 818-26 9 s.

Publikation: Bidrag til tidsskriftReviewpeer review

Hybrid recanalization of superior mesenteric artery occlusion in acute mesenteric ischemia

Sonesson, B., Hinchliffe, R. J., Dias, N. V., Resch, T. A., Malina, M. & Ivancev, K., feb. 2008, I: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists. 15, 1, s. 129-32 4 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Immunohistochemical changes in the expression of HSP27 in exercised human vastus lateralis muscle

Folkesson, M., Mackey, A. L., Holm, L., Kjaer, M., Paulsen, G., Raastad, T., Henriksson, J. & Kadi, F., nov. 2008, I: Acta physiologica (Oxford, England). 194, 3, s. 215-22 8 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

In situ bending of a thoracic stent-graft: a proposed novel technique to improve thoracic endograft seal

Kölbel, T., Lee, T., Ivancev, K., Resch, T. A., Sonesson, B. & Malina, M., feb. 2008, I: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists. 15, 1, s. 62-6 5 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Influence of pain and gender on impact loading during walking: a randomised trial

Henriksen, M., Christensen, R., Alkjaer, T., Lund, H., Simonsen, E. B. & Bliddal, H., feb. 2008, I: Clinical biomechanics (Bristol, Avon). 23, 2, s. 221-30 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

BACKGROUND: Knee joint osteoarthritis is painful and with an overweight of female incidence. The cardinal symptom is pain, which causes compensatory gait changes, and gender differences in pain sensitivity exist. Impact loadings at heel strike during walking are suspected as a co-factor in development of knee osteoarthritis. Thus the purpose of this study was to investigate the influence of experimental muscle pain and gender on generation and attenuation of impact loading during walking.

METHODS: Ten healthy males and 10 healthy females were recruited. Impact loadings during walking were measured using force platforms and accelerometers attached to the tibia and sacrum. Impact ground reaction force peaks and loading rates, and peak accelerations were used to quantify impact loadings. Attenuation was quantified by means of a transfer function between the tibial and sacral accelerometer signals, and the relative peak acceleration reduction. Knee joint kinematics were collected using a three-dimensional movement analysis system. The study was a cross-over study and data were collected before, during, and after experimental vastus medialis pain and a control situation.

FINDINGS: Experimental muscle pain did not affect generation or attenuation of impact loading in either gender. While the impact loading magnitude was similar across genders, lower loading rates and more efficient attenuation were observed in females.

INTERPRETATION: It is concluded that generation and attenuation of impact loadings during walking are independent of quadriceps pain in both genders. The present study does not provide any evidence of the tested variables to address the gender differences in loading rates and attenuation.

Originalsprog Engelsk
Tidsskrift Clinical biomechanics (Bristol, Avon)
Vol/bind 23
Udgave nummer 2
Sider (fra-til) 221-30
Antal sider 10
ISSN 0268-0033
DOI
Status Udgivet - feb. 2008

Ion transporters involved in acidification of the resorption lacuna in osteoclasts

Henriksen, K., Sørensen, M. G., Jensen, V. K., Dziegiel, M. H., Nosjean, O. & Karsdal, M. A., sep. 2008, I: Calcified Tissue International. 83, 3, s. 230-42 13 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Osteoclasts possess a large amount of ion transporters, which participate in bone resorption; of these, the vacuolar-adenosine trisphosphatase (V-ATPase) and the chloride-proton antiporter ClC-7 acidify the resorption lacuna. However, whether other ion transporters participate in this process is currently not well understood. We used a battery of ion channel inhibitors, human osteoclasts, and their subcellular compartments to perform an unbiased analysis of the importance of the different ion transporters for acidification of the resorption lacuna in osteoclasts. CD14(+) monocytes from human peripheral blood were isolated, and mature osteoclasts were generated using RANKL and M-CSF. The human osteoclasts were (1) used for acridine orange assays for evaluation of lysosomal acidification, (2) used for bone resorption assays, (3) used for generation of osteoclasts membranes for acid influx experiments, or (4) lysed in trizol for mRNA isolation for Affymetrix array analysis. Inhibitors targeted toward most of the ion transporters showed low potency in the acidification-based assays, although some inhibitors, such as carbonic anhydrase II and the sodium-hydrogen exchanger (NHE) inhibitors, reduced resorption potently. In contrast, inhibitors targeted at V-ATPase and ClC-7 potently inhibited both acidification and resorption, as expected. We here show evidence that acidification of the resorption lacuna is mainly mediated by V-ATPase and ClC-7. Furthermore, a group of other ion transporters, including carbonic anhydrase II, the NHEs, and potassium-chloride cotransporters, are all involved in resorption but do not seem to directly be involved in acidification of the lysosomes.

Originalsprog Engelsk
Tidsskrift Calcified Tissue International
Vol/bind 83
Udgave nummer 3
Sider (fra-til) 230-42
Antal sider 13
ISSN 0171-967X
DOI
Status Udgivet - sep. 2008

Is newer better? A cross-validation of the Static-2002 and the risk matrix 2000 in a danish sample of sexual offenders

Bengtson, S., apr. 2008, I: Psychology, Crime and Law. 14, 2, s. 85-106 22 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Kriminelt recidiv blandt sædelighedskriminelle

Bengtson, S. & Lund, J., 1 dec. 2008, I: Ugeskrift for Laeger. 170, 49, s. 4035-4039 5 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Little effect of transfer technique instruction and physical fitness training on reducing low back pain among nurses

Warming, S., Ebbehøj, N. E., Wiese, N., Perrild, H. J. D. & Tønnesen, H., 2008, I: Ergonomics. 51

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Originalsprog Engelsk
Tidsskrift Ergonomics
Vol/bind 51
ISSN 0267-4718
Status Udgivet - 2008

Long-term effects of a preoperative smoking cessation programme

Villebro, N. M., Pedersen, T., Møller, A. M. & Tønnesen, H., 1 jul. 2008, I: Clinical Respiratory Journal. 2, 3, s. 175-82 8 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Preoperative smoking intervention programmes reduce post-operative complications in smokers. Little is known about the long-term effect upon smoking cessation.
Originalsprog Engelsk
Tidsskrift Clinical Respiratory Journal
Vol/bind 2
Udgave nummer 3
Sider (fra-til) 175-82
Antal sider 8
ISSN 1752-6981
DOI
Status Udgivet - 1 jul. 2008

Manipulation does not add to the effect of extension exercises in chronic low-back pain (LBP). A randomized, controlled, double blind study

Rasmussen, J. H., Lætgaard, J., Lindecrona, A-L., Qvistgaard, E. & Bliddal, H., dec. 2008, I: Joint Bone Spine. 75, 6, s. 708-713

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Motivation of trauma patients to stop smoking after admission to the emergency department

Weiss-Gerlach, E., Franck, M., Neuner, B., Gentilello, L. M., Neumann, T., Tønnesen, H., Kolbeck, S., Cammann, H., Perka, C., MacGuill, M. & Spies, C. D., 1 jul. 2008, I: Addictive Behaviors. 33, 7, s. 906-18 13 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Every smoker should be offered smoking cessation treatment when they present for clinical care. The Readiness to Change-Smokers (RTC-S) questionnaire and the Heidelberg Smoking History (HSH) are brief questionnaires that divide patients into three stages. The purpose of this study was to prospectively compare the performance of each questionnaire at identifying patients who will successfully quit smoking within one year of Emergency Department (ED) discharge. Out of 1292 injured ED patients nearly half (n = 599, 46.4%) were identified as current smokers. Both questionnaires were given to all 599 subjects, and used to divide patients into three stages. At 12-months postdischarge 306 patients (51.1%) were contacted to determine smoking status. Patients were similarly classified by both tests in only 36% of cases. Concordance between tests was poor (kappa = 0.33). The RTC-S classified fewer patients as ready to quit (A = 13% vs. 22.2%). At 12 month follow-up, 55 patients (17.9%) had stopped smoking. The HSH was more successful to predict quitters. Multivariate logistic regression with respect to smoking cessation resulted in significant impact of HSH (p = 0.024).
Originalsprog Engelsk
Tidsskrift Addictive Behaviors
Vol/bind 33
Udgave nummer 7
Sider (fra-til) 906-18
Antal sider 13
ISSN 0306-4603
DOI
Status Udgivet - 1 jul. 2008

Muskelstyrken hos patienter med fibromyalgi. Et litteraturstudie

Dombernowsky, T., Dreyer, L., Bartels, E. M. & Danneskiold-Samsøe, B., 2008, I: Ugeskrift for Laeger. 170, 4, s. 217-24 8 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Do patients with fibromyalgia (FM) have reduced muscular strength? We examined 22 articles and conclude from the results of these that FM patients have reduced muscular strength in their hands and quadriceps. The material also suggests generalised reduced muscular strength. However, the studies have several methodological shortcomings and future studies should be carefully designed with respect to patients as well as the control group and should be larger. To avoid CNS influence from e.g. fatigue and pain, muscular electro-stimulation may be used to ensure that the actual maximal muscular strength is also measured.
Bidragets oversatte titel Muscular strength in patients with fibromyalgia. A literature review
Originalsprog Dansk
Tidsskrift Ugeskrift for Laeger
Vol/bind 170
Udgave nummer 4
Sider (fra-til) 217-24
Antal sider 8
ISSN 0041-5782
Status Udgivet - 2008

Nonvestibular schwannoma tumors in the cerebellopontine angle: a structured approach and management guidelines

Springborg, J. B., Poulsgaard, L. & Thomsen, J., jul. 2008, I: Journal of Neurological Surgery, Part B: Skull Base. 18, 4, s. 217-27 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Nordic Walking does not reduce the loading of the knee joint

Hansen, L., Henriksen, M., Larsen, P. & Alkjaer, T., aug. 2008, I: Scandinavian journal of medicine & science in sports. 18, 4, s. 436-41 6 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

The use of Nordic Walking (NW) as a rehabilitation modality has increased considerably. NW (walking with poles) is advocated as a healthy physical activity that reduces the load on the knees. Few studies using the techniques of NW exist, and the findings are contradictory. The aim of this study was to investigate whether NW reduces the loadings upon the knee joint compared with walking without poles (NP). Seven experienced female NW instructors volunteered. Three-dimensional gait analyses were performed. Internal flexor and extensor joint moments were calculated using an inverse dynamics approach and the knee joint compressive forces were calculated. No differences in compression or shear forces between NW and NP were found. The peak knee flexion angles were larger during NW (-32.5+/-6.0 degrees) compared with NP (-28.2+/-4.2 degrees). The hip range of motion (ROM) was significantly increased during NW (64.4+/-10.2 degrees) compared with NP (57.8+/-9.7 degrees); no differences in the knee and ankle joint ROM were observed. The changes in the joint angles were not followed by changes in the joint dynamics. The present study does not support the statement that NW reduces the load on the knees.

Originalsprog Engelsk
Tidsskrift Scandinavian journal of medicine & science in sports
Vol/bind 18
Udgave nummer 4
Sider (fra-til) 436-41
Antal sider 6
ISSN 0905-7188
DOI
Status Udgivet - aug. 2008

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