Published in 2011

Tendon-related injuries are a major problem, but the aetiology of tendinopathies is unknown. In tendinopathies as well as during unaccustomed loading, intra-tendinous flow can be detected indicating that extensive loading can provoke intra-tendinous flow. The aim of present study is to evaluate the vascular response as indicated by colour Doppler (CD) activity in both the Achilles and patella tendon after loading during high-level badminton matches. The Achilles tendon was subdivided into a mid-tendon, pre-insertional, and insertional region and the anterior knee tendons into a quadriceps-, patella- and tuberositas region. Intra-tendinous flow was measured using both a semi-quantitative grading system (CD grading) and a quantitative scoring system (CF) on colour Doppler. Intra-tendinous flow in the Achilles and anterior knee tendons was examined in fourteen single players before tournament and after 1st and 2nd match, respectively on both the dominant and non-dominant side. All players had abnormal intra-tendinous flow (Colour Doppler ≥ grade 2) in at least one tendon in at least one scan during the tournament. At baseline, only two of the 14 players had normal flow in all the tendons examined. After 1st match, tendencies to higher intra-tendinous flow were observed in both the dominant patella tendon and non-dominant quadriceps tendon (P-values n.s.). After 2nd match, intra-tendinous flow was significant increased in the dominant patella tendon (P = 0.009). In all other locations, there was a trend towards a stepwise increase in intra-tendinous flow. The preliminary results indicate that high amount of intra-tendinous flow was found in elite badminton players at baseline and was increased after repetitive loading, especially in the patella tendon (dominant leg). The colour Doppler measurement can be used to determine changes in intra-tendinous flow after repetitive loading.
Originalsprog Engelsk
Tidsskrift Knee Surgery, Sports Traumatology, Arthroscopy
Vol/bind 19
Udgave nummer 1
Sider (fra-til) 30-7
Antal sider 8
ISSN 0942-2056
DOI
Status Udgivet - 1 jan. 2011

Experimental knee pain reduces muscle strength

Henriksen, M., Mortensen, S. R., Aaboe, J., Nielsen, T. G. & Bliddal, H., 1 apr. 2011, I: Journal of Pain. 12, 4, s. 460-7 8 s.

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Pain is the principal symptom in knee pathologies and reduced muscle strength is a common observation among knee patients. However, the relationship between knee joint pain and muscle strength remains to be clarified. This study aimed at investigating the changes in knee muscle strength following experimental knee pain in healthy volunteers, and if these changes were associated with the pain intensities. In a crossover study, 18 healthy subjects were tested on 2 different days. Using an isokinetic dynamometer, maximal muscle strength in knee extension and flexion was measured at angular velocities 0, 60, 120, and 180 degrees/second, before, during, and after experimental pain induced by injections of hypertonic saline into the infrapatellar fat pad. On a separate day, isotonic saline injections were used as control condition. The pain intensity was assessed on a 0- to 100-mm visual analogue scale. Knee pain reduced the muscle strength by 5 to 15% compared to the control conditions (P <.001) in both knee extension and flexion at all angular velocities. The reduction in muscle strength was positively correlated to the pain intensity. Experimental knee pain significantly reduced knee extension and flexion muscle strength indicating a generalized muscle inhibition augmented by higher pain intensities. PERSPECTIVE: This study showed that knee joint pain has a significant impact on muscle function. The findings provide evidence of a direct inhibition of muscle function by joint pain, implying that rehabilitative strengthening exercises may be antagonized by joint pain.
Originalsprog Engelsk
Tidsskrift Journal of Pain
Vol/bind 12
Udgave nummer 4
Sider (fra-til) 460-7
Antal sider 8
ISSN 1526-5900
DOI
Status Udgivet - 1 apr. 2011

Expression of NFATc1 is inducible by P2X7 receptor activation in human osteoclasts

Agrawal, A. & Gartland, A., 1 maj 2011, I: Bone. 48, s. S126

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External or internal fixation in the treatment of non-reducible distal radial fractures?

Landgren, M., Jerrhag, D., Tägil, M., Kopylov, P., Geijer, M. & Abramo, A., okt. 2011, I: Acta orthopaedica. 82, 5, s. 610-3 4 s.

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Feasibility of a standardized ultrasound examination in patients with rheumatoid arthritis: Quality improvement among rheumatologists

Ellegaard, K., Torp-Pedersen, S. T., Christensen, R. D. K., Stoltenberg, M., Hansen, A., Lorenzen, T., Jensen, D., Juul, L., Lindegaard, H., Røgind, H., Bülow, P., Cheysider, S., Kowalski, M. R., Danneskiold-Samsøe, B. & Bliddal, H., 2011, I: Annals of the Rheumatic Diseases. 70, Suppl. 3, s. 544 1 s.

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Originalsprog Engelsk
Tidsskrift Annals of the Rheumatic Diseases
Vol/bind 70
Udgave nummer Suppl. 3
Sider (fra-til) 544
Antal sider 1
ISSN 0003-4967
Status Udgivet - 2011

Fluid flow stimulates ATP release from human derived osteoclasts without changing resorption

A, G. & Agrawal, A., 2011, I: Frontiers in Endocrinology. 2

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Originalsprog Engelsk
Tidsskrift Baltic Journal of Comparative & Clinical Systems Biology
Vol/bind 1
Sider (fra-til) 35
Antal sider 44
Status Udgivet - 2011

FoxP3 mRNA splice forms in arthritis patients

Ryder, L. R., 2011, eget forlag.

Publikation: Bog/antologi/afhandling/rapport › Ph.d.-afhandling

Originalsprog Engelsk
Udgivelsessted eget forlag
Status Udgivet - 2011

Fractures and alcohol abuse - patient opinion of alcohol intervention

Pedersen, B., Alva-Jørgensen, P., Raffing, R. & Tønnesen, H., 1 jan. 2011, I: The Open Orthopaedics Journal. 5, s. 7-12 6 s.

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To clarify patient opinions about alcohol intervention in relation to surgery before investigating the effect in a Scandinavian multi-centre randomized trial.
Originalsprog Engelsk
Tidsskrift The Open Orthopaedics Journal
Vol/bind 5
Sider (fra-til) 7-12
Antal sider 6
ISSN 1874-3250
DOI
Status Udgivet - 1 jan. 2011

Funktionsevnemåling

Hendriksen, C. & Avlund, K., 2011, Klinisk Social Medicin og Rehabilitering. København: FADL's Forlag

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Formidling

Originalsprog Dansk
Titel Klinisk Social Medicin og Rehabilitering
Udgivelsessted København
Forlag FADL's Forlag
Publikationsdato 2011
Kapitel 6
Status Udgivet - 2011

Generelle principper for vurdering af den reumatologiske patient i en rehabliteringskontekst

Amris, K. & Lund, H., 2011, Klinisk Reumatologi. Danneskiold-Samsøe, B., Lund, H. & Währens, E. E. (red.). 2 udg. København: Munksgård Danmark, Bind 1. s. 291-299 9 s.

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Originalsprog Dansk
Titel Klinisk Reumatologi
Redaktører Bente Danneskiold-Samsøe, Hans Lund, Eva Ejlersen Währens
Antal sider 9
Vol/bind 1
Udgivelsessted København
Forlag Munksgård Danmark
Publikationsdato 2011
Udgave 2
Sider 291-299
Kapitel 20
ISBN (Trykt) 9788762806726
Status Udgivet - 2011

Hazardous drinkers in Norwegian hospitals - a cross-sectional study of prevalence and drinking patterns among somatic patients

Oppedal, K., Nesvåh, S., Pedersen, B., Daltveit, J. T. & Tønnesen, H., 2011, I: Norsk Epidemiologi. 21, 1, s. 93-98 5 s.

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Originalsprog Engelsk
Tidsskrift Norsk Epidemiologi
Vol/bind 21
Udgave nummer 1
Sider (fra-til) 93-98
Antal sider 5
ISSN 0803-2491
Status Udgivet - 2011

Holistisk-neuropsykologisk genoptræning--dokumentationen mangler

Olsen, T. S., 2011, I: Ugeskrift for Laeger. 173, 22, s. 1595

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Bidragets oversatte titel Holistic-neuropsychological rehabilitation--documentation is lacking
Originalsprog Dansk
Tidsskrift Ugeskrift for Laeger
Vol/bind 173
Udgave nummer 22
Sider (fra-til) 1595
ISSN 0041-5782
Status Udgivet - 2011

Identifying Preliminary Domains to Detect and Measure Rheumatoid Arthritis Flares: Report of the OMERACT 10 RA Flare Workshop

Bingham, C. O., Alten, R., Bartlett, S. J., Bykerk, V. P., Brooks, P. M., Choy, E., Christensen, R., Furst, D. E., Hewlett, S. E., Leong, A., May, J. E., Montie, P., Pohl, C., Sanderson, T. C., Strand, V., Woodworth, T. G. & for the OMERACT RA Flare Definition Working Group, 1 aug. 2011, I: Journal of Rheumatology. 38, 8, s. 1751-1758 8 s.

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Background. While disease flares in rheumatoid arthritis (RA) are a recognized aspect of the disease process, there is limited formative research to describe them. METHODS: The Outcome Measures in Rheumatology Clinical Trials (OMERACT) RA Flare Definition Working Group is conducting an international research project to understand the specific characteristics and impact of episodic disease worsening, or "flare," so that outcome measures can be developed or modified to reflect this uncommonly measured, but very real and sometimes disabling RA disease feature. Patient research partners provided critical insights into the multidimensional nature of flare. The perspectives of patients and healthcare and research professionals are being integrated to ensure that any outcome measurement to detect flares fulfills the first OMERACT criteria of Truth. Through an iterative data-driven Delphi process, a preliminary list of key domains has been identified to evaluate flare. RESULTS: At OMERACT 10, consensus was achieved identifying features of flare in addition to the existing core set for RA, including fatigue, stiffness, symptom persistence, systemic features, and participation. Patient self-report of flare was identified as a component of the research agenda needed to establish criterion validity for a flare definition; this can be used in prospective studies to further evaluate the Discrimination and Feasibility components of the OMERACT filter for a flare outcome measure. CONCLUSION: Our work to date has provided better understanding of key aspects of the RA disease process as episodic, potentially disabling disease worsening even when a patient is in low disease activity. It also highlights the importance of developing ways to enhance communication between patients and clinicians and improve the ability to achieve "tight control" of disease.
Originalsprog Engelsk
Tidsskrift Journal of Rheumatology
Vol/bind 38
Udgave nummer 8
Sider (fra-til) 1751-1758
Antal sider 8
ISSN 0315-162X
DOI
Status Udgivet - 1 aug. 2011

Indførelse af elektronisk patientjournal i akutafdeling

Taran, S. E., Zhan, C., Møller, E. & Schmidt, T. A., 2011, I: Ugeskrift for Læger. 173, 23, s. 1645-1647 3 s.

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Inhaled Nitric Oxide

Afshari, A., 2011, Clinical Evidence in Intensive Care: ESICM Systematic Review Group. 1 udg. Berlin: Medizinisch Wissenschaftliche Verlagsgesellschaft, s. 39–42

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Interleukin-targeted therapy for metabolic syndrome and type 2 diabetes

Maedler, K., Dharmadhikari, G., Schumann, D. M. & Størling, J., 2011, Diabetes - Perspectives in Drug Therapy. Springer Science and Business Media, LLC, s. 257-278 22 s. (Handbook of Experimental Pharmacology, Bind 203).

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Introduction--microorganisms and the locomotor system

Wollheim, F. A. & Locht, H., 2011, I: Best Practice & Research: Clinical Rheumatology. 25, 3, s. 333-5 3 s.

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Originalsprog Engelsk
Tidsskrift Best Practice & Research: Clinical Rheumatology
Vol/bind 25
Udgave nummer 3
Sider (fra-til) 333-5
Antal sider 3
ISSN 1521-6942
DOI
Status Udgivet - 2011

Is it possible to reduce the knee joint compression force during level walking with hiking poles?

Jensen, S. B., Henriksen, M., Aaboe, J., Hansen, L., Simonsen, E. B. & Alkjaer, T., 2011, I: Scandinavian journal of medicine & science in sports. 21, 6, s. E195-E200

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Walking with hiking poles has become a popular way of exercising. Walking with poles is advocated as a physical activity that significantly reduces the loading of the hip, knee and ankle joints. We have previously observed that pole walking does not lead to a reduction of the load on the knee joint. However, it is unclear whether an increased force transmitted through the poles can reduce the load on the knee joint. Thus, the purpose of the present study was to investigate if an increased load transmitted through the arms to the poles could reduce the knee joint compression force during level walking with poles. We hypothesized that an increased pole force would result in a reduction of the knee joint compression force. Gait analyses from 10 healthy subjects walking with poles were obtained. The pole force was measured simultaneously during the gait analyses. The knee joint compression forces were estimated by using a biomechanical knee joint model. The results showed that the subjects were able to increase the pole force by 2.4 times the normal pole force. However, this did not lead to a reduction in the knee joint compressive force and we rejected our hypothesis. In conclusion, the use of poles during level walking does not seem to reduce knee joint compressive loads. However, it is possible that the use of poles in other populations (e.g. osteoarthritis patients) and in terrain would unload the knee joint. This should be investigated in the future.
Originalsprog Engelsk
Tidsskrift Scandinavian journal of medicine & science in sports
Vol/bind 21
Udgave nummer 6
Sider (fra-til) E195-E200
ISSN 0905-7188
DOI
Status Udgivet - 2011

Job Satisfaction, Work Environment, and Rewards: Motivational Theory Revisited

Sell, L. & Cleal, B., mar. 2011, I: Labour. 25, 1, s. 1-23 23 s.

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